NEUROBION: WHAT IS IT FOR, INDICATIONS AND CONTRAINDICATIONS - GEOGRAFÍA - 2025

Neurobion is an anti-inflammatory, analgesic, antineuritic and antineuralgic drug. It is characterized by being composed of type B vitamins (B1, B6 and B12 mainly).

That is, it can help relieve bodily discomfort such as cramps, tingling, muscle weakness or burning. In turn, thanks to its vitamin components, it is used to treat anemia, nutritional deficiency, loss of myelin or fight cases of neurasthenia.

The only way to take a correct dose of Neurobion is through an accurate clinical diagnosis in which it is determined exactly what type of discomfort the patient has. However, in adults, Neurobion tablets / capsules are often prescribed one to three times a day, depending on the doctor's prescription.

Under no circumstances should the recommended dose be exceeded or increased, unless the specialist deems it necessary.

What is the Neurobion for?

Neurobion is widely used to combat inflammation of the tissues, the sensation of pain, inflammation of the nerves and neuralgia, that is, those continuous but not necessarily inflammatory pains that extend into a specific nerve and its respective branches. Neurobion comes in ampoules, lozenges, or capsules.

Neurobion is used as an auxiliary treatment for both neuritis and neuralgia, which are both ailments related to inflammation of the nerves.

It is also used in conditions such as rheumatism, arthritis, spondyloarthrosis (also known as EDD, or Degenerative Disc Disease), spondylitis (a form of chronic arthritis that affects one or more of the vertebrae of the spine) and gout.

Composition

Neurobion is mainly characterized by being composed of vitamin B1 (common name given to thiamine nitrate), vitamin B6 (ibidem, but pyridoxine hydrochloride) and vitamin B12 (ibid, but cyanocobalamin). This composition comprises each dragee, capsule or ampoule separately.

In any case, it is worth noting that the amounts and additional ingredients may vary according to the presentation (some contain substances such as diclofenac sodium, excipients, etc.).

Pharmacology

The pharmacological action of Neurobion occurs in three ways. In vitamin B1, it helps to solve the lack of thiamine in the body, which is responsible for the lactic acid that accumulates in the body and that affects muscle, circulatory, bone and nervous performance.

Vitamin B6 compensates for the lack of pyridoxine that causes nerve problems, apart from other tissue damage. Vitamin B12, for its part, is useful to reduce neurological damage that can occur in degenerative pathological processes.

As a whole, these three vitamins (that is, B1, B6 and B12), integrated in Neurobion, can regulate the metabolic activity of enzymes, whose levels in the body can rise with an increase in the dose above the requirements newspapers.

Both in the short and long term, changes are felt in the metabolism, which experiences a saturation and then a release of these enzymes (coenzymes and apoenzymes).

Also, it is possible that higher doses of Neurobion can eliminate or soothe pain, which is known as the analgesic effect.

In these cases, the neuropathies can be mitigated and the damage that has been caused in the nervous tissue can also be repaired thanks to the stimulation of the synthesis of nucleoproteins, that is, of the compounds that combine proteins with nucleic acids (the DNA and RNA).

Contraindications

The administration of Neurobion is absolutely contraindicated in the following cases:

• Allergy or hypersensitivity to the components.
• Patients with Parkinson's disease, as long as they are taking levodopa alone.
• Children under 6 years (to find out whether or not the older child can take Neurobion, consult the pediatrician).
• During pregnancy and lactation.
• Kidney or liver failure.
• Digestive system disorders: gastritis, duodenal and gastric ulcers, esophagitis.
• Elderly of advanced age.

Adverse reactions

In higher than normal doses, Neurobion can cause disturbances in the nervous system. Common reactions that have been seen in patients include diarrhea, vomiting, nausea, fatigue, vertigo, and headache.

Only in very few cases has ulcerative colitis and gastrointestinal bleeding worsening, as well as irritability, seizures, insomnia, tinnitus, hives, and momentary reddish skin eruptions (exanthemas) have been found.

There are also rare or exceptional cases of reactions to Neurobion, such as photosensitivity, hair loss (alopecia), kidney failure, liver dysfunction, inflammation of the kidneys (nephritis), and blood in the urine (hematuria).

This list is also joined by several additional conditions, such as decreased white blood cells (leukopenia), reduced platelets (thrombocytopenia), and anemia, among others.

Precautions

Before its consumption by the patient, Neurobion medication requires these considerations and preventive measures, which will be studied in one case or another by the doctor, weighing the pros and cons of this drug:

• Neurobion contraindications, with their adverse reactions and interactions (see sections 4, 5 and 7 of this article).
• Presence of disorders linked to the central nervous system, which may prevent the patient from concentrating on the use of machines or driving vehicles.
• Existence of celiac disease and diabetes in the patient (there are presentations of this drug that contain gluten and sugar).

Interactions

Neurobion has reactions with drugs and other substances, such as acetaminophen, insulin, heparin, valproic acid, and levodopa.

The various interactions of the Neurobion can have consequences on the efficacy of medications already being taken and, moreover, on the patient's health.

Attention

This article is only intended to give general information about Neurobion, hence there will be no widespread use of pharmaceutical terminology. Since Neurobion is a product that comes in different presentations, it will be discussed globally. It should be noted that Neurobion is a registered trademark in the name of Merck, so this writing is not an official publication of the company and its author does not act on its behalf.

It is worth saying that you consult a specialist first if you have a condition that can be treated with Neurobion; do not take it if you don't need it or if your doctor hasn't told you to.

It is also important to limit what the leaflets that are printed on all medicines say: you must always go to the doctor if there are adverse effects, if you have an allergy to any of its components and if you are pregnant or breastfeeding. See the references section for more details.]

References

1. Dolo Neurobion®. Lima Peru. Peruvian Society of Cardiology, Merck Peruana SA Accessed on January 26, 2017, at: sopecard.org.
2. Juárez, LM (No year). Pharmacological Review. Antianemic. Mexico DF, Mexico. National Autonomous University of Mexico, Department of Family Medicine. Consulted on January 26, 2017, at: facmed.unam.mx.
3. McVan, Barbara (1995). Pharmaceutical references: reference manual for health professionals (Francisco Balderrama Encimas, trad.). Mexico DF, Mexico. Modern Manual.
4. Neurobion® 5000. Merck (2015). PRVademecum. Clyna SA Consulted on January 26, 2017, at: pe.prvademecum.com.
5. Neurobion Ampoules (2017). Metn, Lebanon. HCP-Meppo. Consulted on January 26, 2017, at: meppo.com.
6. Neurobión - CECMED (2014). Havana Cuba. Ministry of Public Health of Cuba; Center for State Control of Medicines, Medical Equipment and Devices. Consulted on January 26, 2017, at: cecmed.cu.
7. Neurobion - Merck Consumer Health (2016). Darmstadt, Germany. Merck. Accessed January 26, 2017, at: merck-consumer-health.com.
8. Rodríguez Carranza, Rodolfo (1999). Academic Vademecum of Medicines (3rd ed.). Mexico DF, Mexico. MacGraw-Hill Interamericana.