DOMEBORO: WHAT IS IT FOR, INDICATIONS AND CONTRAINDICATIONS - MEDICINE - 2025

The Domeboro is a medicament comprising a solution of calcium acetate and aluminum sulphate, which is used for treating allergies and skin conditions. It was developed by the surgeon Karl Heinrich August Burow, who made a preparation with aluminum sulfate, acetic acid, precipitated calcium carbonate and water, which was initially used for the treatment of varicophlebitis.

Skin allergies are an exaggerated immune reaction or response of the body to the presence of irritants, which are known as allergens. Generally, this allergic reaction manifests itself with the appearance of skin rashes, redness, itching, hives, peeling skin or blisters.

This solution was initially called Burow's water. It was later perfected by Dome Labs and its trade name Domeboro is derived from.

Pharmaceutical form and formulation

Domeboro comes as a powder with a pH 4.2. The content of each sachet is 0.8008 g of calcium acetate, 1: 1352 g of aluminum sulfate and excipient cbp.

What is the Domeboro for?

Domeboro is an astringent and emollient that provides a soothing wet cure used to treat inflammatory skin conditions, which can be caused by an allergic reaction.

These allergic reactions can appear as a result of insect bites, poisonous plants, erosions and skin inflammations.

It is also possible that a contact dermatitis appears due to allergy to jewelry containing nickel, due to allergic reactions to soaps and detergents. Another of the uses of Domeboro is in the treatment of discomfort caused by athlete's foot.

Pharmacokinetics and pharmacodynamics

The medicine can be used if it is desired to obtain an astringent, decongestant or sedative effect on burning and itching.

Its consistency is non-occlusive, allowing the skin to breathe. It can be used in cases of acute dermatosis, since its astringent action is not absorbed by the skin.

Poisonous plant rash treatment

Domeboro is ideal for treating rashes caused by contact with poison ivy, poison sumac, or poison oak. The therapeutic action of Domeboro helps relieve irritation, burning and itching caused by contact with these plants.

The irritation caused by poisonous plants is the result of coming into contact with an oil called urushiol. Situation that can occur when touching or rubbing the leaves and stems of the plant, which have this oil.

Generally, the allergic reaction is not immediate, and irritation sometimes does not appear the first time you come into contact with this oil. However, the immune system works by preparing a defense in case of being attacked by the same substance again.

This immunological work causes that upon coming into contact with urushiol again, an allergic reaction occurs as a defense of the organism against the offending agent.

Sometimes it can take 24 to 72 hours after exposure to the poison before irritation, blisters, red bumps, burning, inflammation, and swelling of the skin appear.

Likewise, there are other situations in which the skin rash does not appear until 5 days after having contact with the irritant agent, and it can also occur in phases and last between two and three weeks, having its peak between the fourth and seventh day.

Presentations

The Domeboro comes in boxes of 12 2.2 g sachets. Also in a refreshing gel, which provides the same effectiveness as the solution that is achieved by dissolving the contents of the sachets.

Other uses

Like soap

To use it as soap, it is necessary to dissolve between 1 to 3 packages of 16 oz (450-480 ml) each in water, which can be cold or hot. After being dissolved it is ready to be used.

Depending on the number of sachets used, mixtures of 0.16%, 0.32% and 0.48% aluminum acetate can be obtained. Lather the affected area for an estimated 15 to 30 minutes, or as long as your doctor has prescribed. Once used, discard the solution.

As a wet compress

• Dissolve 1 to 3 sachets of 0.16% in warm or cold water
• Shake until you get a homogeneous mixture
• Do not filter
• Depending on the amount of sachet you use, the concentration of aluminum acetate will increase by the same amount.
• Once the powder is completely dissolved, it is ready to be used.

Soak a clean, soft cloth in the solution and apply loosely to the affected skin area. Let it act for a period of time between 15 and 30 minutes, or according to the time indicated by the doctor. Discard the solution after use is complete.

Contraindications

Contact with the eyes should be avoided, keep out of the reach of children and if you are pregnant or breastfeeding, discontinue use if you have hypersensitivity to the components of the formula. Prolonged use can cause dry skin.

Drug interactions or alteration of laboratory test results

No drug and other interactions have been reported to date and there is no evidence of alterations in laboratory tests due to its use.

With the use of Domeboro, quick and effective relief from the unpleasant symptoms of skin conditions can be achieved in a more effective way than ordinary creams and lotions.

Due to its astringent action, it gently dries out rashes, reduces blisters and redness, calming the urge to scratch, which can cause additional complications.

Domeboro has been used to treat skin conditions for over 50 years with considerable success. However, one must be aware of other symptoms that may be triggered by the allergic process, such as difficulty breathing or if there is infection in the skin lesions.

Also, if the rash is spread over your body, you have swelling in the eyes or throat, or if the condition worsens after about seven days. In case any of these situations occurs, it is necessary to seek medical help immediately.

References

1. Medline Plus. (2017). Retrieved from medlineplus.gov.
2. Rinzler, C. (2009). The Encyclopedia of Cosmetic and plastic Surgery.
3. Rite Aid Pharmacy. (2001-2016). Domeboro Astringent Solution, Powder Packets, 12 packets. Retrieved from riteaid.com.
4. Web MD. (2005-2017). Poison Ivy, Oak, and Sumac - the Basics. Retrieved from webmd.com.
5. com (2017). Poison Oak and Poison Sumac Symptoms, Treatment and Prevention. Retrieved from domeboro.com.
6. com (2017). How to use Domeboro. Retrieved from domeboro.com.